Biochemistry is perhaps the most fascinating subject as it deals with the chemical language of life, be it human, animal, plant or microorganism. No other science subject has as much application as biochemistry to the disciplines of medicine, dentistry, health, veterinary, bioengineering and technology. This necessitates a totally different outlook for the biochemistry subject. Biochemistry broadly deals with the chemistry of life and living processes. It is the most rapidly developing and most innovative subject in medicine. Biochemical research has amply demonstrated that all living things are closely related at the molecular level. Biochemistry helps in knowing the building blocks – proteins, carbohydrates, fats, nucleic acids etc. It is necessary for dental students to understand various biochemical mechanisms so as to correlate or identify with the pathological units. These molecules are necessary to know or understand various laboratory investigations and its relevance in general practice. It is situated on the fifth floor of the dental college.